Cellucor C4 Original Pre-Workout Supplement Review – In-Depth Ingredient, Benefit and Price Analysis

C4 is Cellucor's flagship product - and the Original version is their best seller. It's a popular pre-workout supplement with beta-alanine, creatine, caffeine and various other ingredients, along with host of vitamins.

In this C4 Original review, I'll take a closer look at this pre-workout supplement to find out whether it lives up to the hype. I'm particularly interested in the ingredients profile and whether the doses are backed by clinical data. Let's get started!

Basic Overview of C4 Original

Cellucor C4 is one of the most popular brands of pre-workout supplement in the US. C4 is actually a range of supplements, including Sport, Extreme, Ultimate, 50x, Gen 4, Ripped and various others, but this review focuses on C4 Original.

According to Cellucor, C4 Original aims to provide the following benefits:

  • Improved endurance and energy from beta-alanine and caffeine
  • Enhanced focus via the caffeine and L-Tyrosine complex
  • Stronger pumps due to nitric-oxide enhancers

There's no doubt that C4 Original is a popular option. It's used by millions of people and is even America's top-selling PWO. As we all know, popularity and marketing hype doesn't always equal quality though. So, let's take a closer look at the ingredients, doses and taste of the C4 supplement.

Ingredients Profile and Formula

Ingredients profile of C4 preworkout

Ingredients list for C4 Original. Other versions have different ingredients profiles.

The Cellucor official website lists C4 Original as providing "explosive energy," "heightened focus" and "an overwhelming urge to tackle any challenge."

These are exciting claims, but are they backed by science?  After all, when you strip away the marketing, hype and popularity of any supplement, its effectiveness rests entirely on the ingredient profile.

While certain ingredients have synergistic properties, these are often over-hyped. That makes it relatively easy to judge the effectiveness of a pre-workout just by looking at its list of ingredients and doses.

How does C4's ingredient list compare to others though?

The first thing to note is that C4 Original contains a proprietary "Explosive Energy Blend."

This is an instant warning sign for me. I'm not a fan of proprietary blends in any supplement. I want to know exactly what I'm taking with every dose, and I'm guessing you do too.

With that said, most of the important ingredients of C4 Original are transparently listed (including caffeine which is part of the proprietary blend). The exception is L-Tyrosine, but I'll get to that in a moment.

The second thing to note is that C4 Original doesn't contain L-Citrulline. I consider citrulline to be a key ingredient in a modern pre-workout supplement, as I mentioned in my guide to pre-workouts, so this is another negative for C4. Cellucor has included Arginine as an alternative NO booster, but it's not as effective.

With these warnings out of the way, here's an overview of its most important ingredients and doses:

  • Beta-Alanine (1600mg). Beta-Alanine is an amino acid that regulates how much carnosine is stored in muscles. It's a safe and effective pre-workout ingredient, and can help reduce fatigue, increase workout capacity and allow you to workout for longer. While it's great that C4 Original includes Beta-Alanine, the 1600mg is much lower than the 4000mg included in PreSeries Bulk or the 4800mg in Legion Pulse.
  • Creatine Nitrate (1000mg). Creatine has been proven to increase endurance, build more strength and minimize muscle damage. 1000mg is a relatively low dose (the standard recommendation is 5mg per day), so you'll want to supplement it separately. This form of creatine also provides nitrate, which may help blood flow and muscle pumps.
  • Arginine (1000mg). L-Arginine is an amino acid that regulates blood flow and nitric oxide levels. It's a popular choice for pre-workouts, but has poor absorption in the intestines. L-Citrulline does a better job of elevating arginine levels than taking L-Arginine directly, which is why I prefer it. With that said, L-Arginine may still boost nitric oxide production, which can increase performance and reduce muscle soreness.
  • Caffeine (150mg). Caffeine is great for boosting endurance - plus it might even have an effect on strength. 150mg is about right for caffeine in a pre-workout, as it's enough to get a noticeable boost without excessive jittering.
  • L-Tyrosine (Unlisted Dose). L-Tyrosine has been shown to reduce stress. It may also improve mood and enhance cognitive function. As it's part of C4 Original's "Explosive Energy Blend," however, the dose isn't listed. This makes it impossible to judge whether it's included at a clinically backed dose.
  • Vitamin Complex. C4 Original contains a range of vitamins, such as B12, B3, C and B9 (folic acid). These are nice to have but not essential unless you're deficient.

As you've probably guessed by now, I think C4 Original has a mediocre ingredients list. It's not terrible and will provide a notable boost in energy while reducing fatigue, but there are much better options on the market. The most important ingredients are caffeine, creatine, beta alanine and tyrosine, which are all proven to provide benefits during or after a workout - but the doses are relatively low.

There are also a host of both natural and artificial flavors (such as sucralose). Many newer pre workout supplements have an all-natural ingredients list, but this isn't the case with C4.

There are some good parts of C4 Original, such as the Beta Alanine, but it's missing some important ingredients (L-Citrulline and Betaine in particular). The ingredients aren't always included at clinically-proven doses either.

Taste, Dosing & Mixability

One of the advantages of C4 Original is that it tastes great - at least compared to most pre-workouts! It's not too sweet and is relatively pleasant to drink.

It's also available in a variety of different flavors. These include Cherry Lemonade, Fruit Punch, Green Apple, Watermelon, Orange Burst and Pink Lemonade. My favorite is Juicy Candy Burst (although I haven't tried them all), but you'll probably want to experiment.

Cellucor recommends taking one scoop with 4-6 fl.oz. of water around 30 minutes before your workout. This provide enough time for the caffeine and other ingredients to kick in.

Once you've assessed your tolerance, there's the option of increasing the dose to 2 scoops before a workout (don't take any more than this though).

How Effective is This Pre-Workout?

To put it bluntly, I'm unimpressed by C4 Original. It might be a popular pre-workout supplement, but it's far from the best.

With that said, it will provide some positive effects. The Beta-Alanine, in particular, can help reduce fatigue and increase workout capacity (although I would have liked a higher dose). The caffeine also acts as a stimulant, although this is found in almost every pre-workout. Arginine may have benefits too, particularly for muscle pump and blood flow.

There's also the option to double dose. This provides a huge 300mg hit of caffeine, so it'll certainly wake you up. Make sure you assess your tolerance with a single scoop before you try this though.

Price and Value for Money

So far, I've been quite harsh on C4 Original. I don't think it provides the best ingredients at the right doses, so it's hard to recommend it over some of the great pre-workouts that are now available.

The price is an area where C4 Original shines though. You can buy a tub of 30 servings for $30, or 60 servings for $49.99. This means the cost per serving is $0.83 - $1, which is considerably cheaper than many pre-workouts. Legion Pulse, for example, costs close to double.

Even so, it's hard to say C4 Original provides value for money. PreSeries Bulk has a much better ingredients list and can be bought for around $1.35 per serving. The extra cost is worth it if you want to maximize performance.

The Good:

  • Relatively inexpensive
  • Includes beta-alanine for reduced fatigue and increase workout capacity
  • Widely available

The Bad:

  • Incomplete ingredients list
  • L-Arginine instead of the more effective L-Citrulline
  • Low doses of important ingredients
  • times-circle-o
    Has a proprietary blend
  • times-circle-o
    Contains artificial sweeteners


Should I Be Worried About C4 Side Effects?

I say this in every review, but it's worth repeating: any supplement can cause potential side effects. Whether you experience any depends on your tolerance and genetics, which is why it's important to assess a pre workout at a lower dose. I also recommend reading the instruction booklet carefully and talking to your doctor before starting any new supplement.

C4 Original doesn't include any of the worst offenders when it comes to side effects though. Ingredients like DMAA, which is now banned in the US, can cause severe side effects, but they aren't included in C4 Original.

One of the most common side effects of any pre-workout with beta-alanine is tingling in the skin. C4 Original doesn't have a huge dose of beta-alanine, but this side effect is still something to be aware of.

If you notice any side effects, you should stop using a supplement until you've spoken to a medical professional.

Do I Need to Cycle It?

As with all pre-workout supplements that contain caffeine, you should cycle off C4 Original every 6-8 weeks. When cycling, don't consume any caffeine or stimulants, so your body can "reset."

Where Can I Buy It?

Unlike some of the more exclusive pre-workout supplements, C4 Original can be bought at most retailers. This includes Amazon, Bodybuilding.com, GNC, Walgreen, CVS, Walmart, Vitamin Shoppe and the official C4 website.

It's common to find C4 Original being sold at discount rates. It's already a relatively cheap pre-workout, but if you can find a discount deal it might be worth picking up. C4 Original is also sold in most countries, such as the UK, Australia, New Zealand and Canada.

C4 Original vs C4 Sport - What's The Difference?

Another of Cellucor's most popular pre-workout supplements is C4 Sport. While both Sport and Original are part of the C4 range, they have different ingredient list.

The biggest difference is that Sport's ingredients are almost entirely a proprietary mix (known as performance blend and concentrated energy). While it contains similar ingredients, such as beta-alanine, arginine and caffeine, the quantities of ingredients are not listed. This makes it almost impossible to recommend. If you're not sure which to buy, I recommend sticking with Original.

C4 Original vs C4 Ripped - What's the Difference?

Unlike Original, C4 Ripped is designed specifically for people who want to lose fat without burning muscle. This requires a proper diet (including managing calories, protein, carbs and fats), workout routine and mindset - but supplementation can help too.

In many ways, Ripped has a similar ingredients label to Original. It includes the "Explosive Energy Blend" proprietary mix, along with 1600mg of beta-alanine. The additional "Ripped Blend" for losing weight, however, includes ingredients such as green tea extract, L-Carnitine and Cayenne, and it doesn't include creatine. Again, I'm not a fan of supplements that don't include ingredient quantities on their labels.

Summary & Rating

Cellucor C4 Original might be a popular pre-workout supplement, but I think it's over-hyped. It has a mediocre ingredients profile that misses many important ingredients, including L-Citrulline. The doses are also relatively small, so you may not get the full benefits of the ingredients it does containC4 Original is far from the worst pre-workout supplement on the market, and it's available for a great price, but there are much better options. To see which I recommend instead, check out our main PWO page.

Cellucor C4 Original Pre-Workout

Cellucor C4 Original Pre-Workout



Focus & Energy


Pump & Fullness


Strength & Endurance


Value For Money